Friday, September 03, 2010
 
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The Link Between Profitability and Oxidative Balance

An animal’s oxidative balance is one of the many factors that can limit milk production and the producer’s bottom line.

Signs of Oxidative Stress
Dealing with oxidative stress requires more energy from the animal that could be used for milk production, growth, longevity and overall animal productivity. Clinical signs can include retained placenta, udder edema and mastitis, as well as delayed first estrus, delayed first breeding and repeat breeding resulting from failure to conceive or from early embryonic death. For producers, this means increased calving intervals, lowered production and, ultimately, culling of cows for failure to breed. All of these clinical signs are costly and reduce profitability for the dairy producer.

Causes of Oxidative Stress
There are many causes of oxidative stress that can cost a producer money. Disease challenges such as bacterial and viral pathogens can be linked to oxidative stress. Fast growth, early lactation and obesity can also elevate oxidative stress. Environmental conditions, such as heat stress, increase oxidative stress. Finally, the diet plays a key role. Vitamin and mineral imbalances can be linked to oxidative stress as well.

   
What Happens
There is a natural balance between free-radical formation and the defense system in both humans and animals. For a dairy cow to stay healthy the systems should stay in balance. But when the body is under stress, free radicals can get out of balance. When this system is out of balance, the body initiates an oxidative chain reaction, resulting in oxidative stress. Peroxidative damage can occur in lipids and macromolecules, which can cause free-radical formation. Those changes in cellular membranes can modify metabolic pathways with altered physiology and pathology, which can lead to decreased efficiency and premature cell death. Once critical structural damage occurs, antioxidants may no longer be able to repair the problems. Understanding proper balance could help reduce stress and prevent some of the greatest problems animals face — the same challenges that affect the dairy producer’s bottom line.
   
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